Renal Acid-Base Transport: Old and New Players
نویسندگان
چکیده
منابع مشابه
Renal acid-base transport: old and new players.
Systemic acid-base homeostasis is the product of complex interactions between metabolism, regulated exhalation of CO2 by the lungs and acid or base excretion by the kidneys. The importance of renal acid-base transport has been highlighted by mutations identified in several proteins involved in this task in patients with inborn forms of renal tubular acidosis. The underlying mechanisms of diseas...
متن کاملAcid-base transport in pancreas—new challenges
Along the gastrointestinal tract a number of epithelia contribute with acid or basic secretions in order to aid digestive processes. The stomach and pancreas are the most extreme examples of acid (H(+)) and base (HCO(-) 3) transporters, respectively. Nevertheless, they share the same challenges of transporting acid and bases across epithelia and effectively regulating their intracellular pH. In...
متن کاملAcid-base transport by the renal proximal tubule.
One of the major tasks of the renal proximal tubule is to secrete acid into the tubule lumen, thereby reabsorbing approximately 80% of the filtered HCO3- as well as generating new HCO3- for regulating blood pH. This review summarizes the cellular and molecular events that underlie four major processes in HCO3- reabsorption. The first is CO2 entry across the apical membrane, which in large part ...
متن کاملPotassium transport across renal distal tubules during acid-base disturbances.
~MALNIC, GERHARD, MARGARIDA DE MELLO AIRES, AND GERHARD GIEBISCH. Potassium transport across renal distal tubules during acid-base disturbances. Am. J. Physiol. 221(4) : 1192-1208. 197 1 .-Free-flow samples of tubular fluid (TF) were collected from superficial nephrons of rat kidneys for the analysis of potassium (K), pH, bicarbonate and inulin-W. Rats were subjected to metabolic or respiratory...
متن کاملMetabolism and Cancer: Old and New Players
1 Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (LBMCC), Hôpital Kirchberg, 9 rue Edward Steichen, L-2540 Luxembourg, Luxembourg 2 Laboratory of Biochemistry and Cellular Biology (URBC), NAmur Research Institute for LIfe Science (NARILIS), University of Namur, 5000 Namur, Belgium 3Cancer Chemoprotection Program, Linus Pauling Institute, 307 Linus Pauling Science Center, Oregon Sta...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nephron Physiology
سال: 2006
ISSN: 1660-2137
DOI: 10.1159/000090217